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Catastrophic failures of the pharmaceutical industry



Every time we see a doctor or prescribe medication, we put our lives in the hands of others. It is an unspoken agreement that we have concluded and we agree. After all, most of us do not know how to do medicine, unless you are a kind of villain.

We also seem to agree with all the side effects that modern medicine causes. They take a pill for depression, which can cause suicidal thoughts and … depression. You are taking a new drug for arthritis and it is causing a dislocation of your jaw. It's unfortunate, but will you create another miracle drug in your bathtub? Probably not. Strangely enough, some pharmaceutical companies have come up with products that not only look like they've been made in a bathtub, but that were unsafe for humans. Here are some of the worst culprits.

1
0th Heparin Recall

Heparin is a blood thinner commonly used in dialysis that keeps veins and arteries free of blood clots. It's also made partly from pig intestine, so it does. One problem that arose in the production of the normally very useful drug was that there was not enough heparin in the US, so much of it was imported from China.

Too bad that part of it was incredibly contaminated. According to some research, it was found that a Chinese company shipped soiled batches to the US causing up to a hundred deaths. Particularly disturbing is that the contaminated items have gone through several stringent quality controls. Scientists are trying to find a better way to make a sort of synthetic heparin because the world is up to 70 percent of the world's heparin dependent on China.

. 9 Elixir Antibiotic (led to the founding of the FDA) – 100 dead

In 1937, President Franklin Roosevelt received a letter from a mother whose child had died after receiving a dubious drug called elixir sulfanilamide. It was touted as one of the first true antibiotics in the world. The problem was that the mixture contained a poison called diethylene glycol.

Almost immediately patients began to experience everything from nausea, kidney failure, to coma. 107 patients died from taking Elixir sulfanilamide. The man who created it took his life two years later, devastated by the death toll. If a good cause came about because of the tragedy, it was the cornerstone of today's Food and Drug Administration, which was founded shortly thereafter.

. 8 Epidural Steroids 2012 Meningitis Outbreak

A Massachusetts facility that produced a steroid called methylprednisolone acetate was the focus of a terrible series of events that took place in 2012, which initially dealt with knowing it and made a callback in September of the same year.

At this time, the extent of her guilt was known [19659-06]. They founded a $ 100 million fund the following year to pay victims for their polluted product. Twenty states in the US reported contaminated steroids and over 750 cases of meningitis directly related to the drug. 64 people died from the onset of the disease. The owners of the pharmacy were arrested under 14 people, and some were even charged with second-degree murder. This happened after the company filed for bankruptcy and even alleged that the cleaning company had been involved in the drug poisoning.

. 7 Panama uses antifreeze for cough syrup

It seemed a good idea for the Panama Social Security Institute to distribute cough syrup to the country's poor population. But at least 20,000 were distributed to people without being tested, and a simple mistake of not reading any ingredient could have prevented a catastrophe.

While mixing the cough syrup, a component called was added to diethylene glycol when drug manufacturers thought they would use a simple sugar substitute. What they were actually interfering with was part of the antifreeze. What, say most doctors, is terrible for a cough. And to stay alive. Between 60 and 300 people died because the manufacturers of cough syrup falsely ordered a wrongly labeled bottle. And all this could have been avoided if even rudimentary tests had been done on the drugs.

. 6 The Bextra Settlement

Bextra was an anti-inflammatory drug marketed by Pfizer. However, the analgesic did not last long, as people quickly suffered from heart problems and there were even reports of a deadly skin condition called Stevens-Johnson syndrome. In 2005, the FDA ordered the drug maker to remove Bextra from stores . But that was not all.

In the end, Pfizer paid one of the largest settlements in history for the Bextra fiasco. $ 4.85 billion for patient claims and more for fraudulent marketing and other class actions. They paid off the mammoth settlement without ever having to acknowledge wrongdoing.

. 5 DES estrogen drug

A synthetic estrogen type sold to women in the mid-20th century. Up to 10 million women took it during their pregnancy, believing that it would help curb miscarriage. Diethylstilbestrol was touted as a panacea to help women deliver babies, but instead estrogen penetrated into everything, including the blood of the fetus itself [1965-9016].

At birth, many of these children had abnormalities in their reproductive organs. Many would turn out to be infertile and, in the end, much more likely to develop various forms of cancer. In particular, what DES was created for (to reduce miscarriages) has increased the likelihood of miscarriages. Armed with this knowledge in 1958, the FDA allowed the drug to be used for another 12 years. They would ban his other use, the fattening of chickens, before taking them off the market for human consumption.

. 4 Broken Breast Implants in France Related to Cancer

Poly Implant Prosthesis designed and manufactured breast implants in France and was indeed one of the world's leading manufacturers of such products. When they began to cut corners in their work, the extent of their laziness was discovered for a decade.

It has been found that 30,000 women in France and surrounding countries have received defective implants during this period. Instead of using medical fillers in breast implants, the company used industrial silicone, saving millions of dollars each year. The same silicone is usually used for computer parts and electronics. Their "savings" also led to housing being broken, which can cause cancer.

. 3 Bayer HIV crisis

Hemophilia is a condition in which a person's blood does not clot normally and even a minor injury becomes a bloodbath. A drug that prevents this would be a godsend. When the pharmaceutical company Bayer (try aspirin!) Developed a drug for this purpose in the early 1980s, it looked like it could pave the way.

Unfortunately, in the early 1980s, there was also a mysterious disease known as HIV that spread. Bayer found that the drug was sometime contaminated with the HIV virus and began heat-treating the drug in 1984 to kill it. The thing is, they still had some spoiled drugs lying around. Instead of doing the superhuman thing and destroying it with fire, they decided to sell the rest to poor countries in Latin America and Asia. At least a hundred hemophiles in Asian countries have AIDS, and thousands around the world have contracted the contaminated product. Bayer and others paid about $ 600 million for their problems, but swear that they are "ethical" and "humane."

. 2 Fen-Phen

There was diet pills in the 1980s and '90s that the FDA silently ignored. Manufacturers of the pills must passively state that their products do not have the FDA seal of approval, and everyone has allowed the trick to continue.

Fen-phen was a bit different. It promised to end obesity. The doctors were absolutely crazy about the stuff, and in 1996 issued 18 million prescriptions for the drug. The drug Fen-Phen also reduced appetite and made the body burn calories faster. We found out that people's heart valves were broken. This is of course much better than being fat. The manufacturer of the drug, American Home Products, had to spit $ 3.75 billion. A total of 175.00 claims were filed against AHP who knows how many were actually paid. And this was not even the first time that the company was conducting legal settlements and class actions in hot water: they had to spend $ 54 million the same year as the Phen settlement because they sold birth control equipment with unknown side effects.

. 1 Thalidomide Drugs in the 1950s and 1960s

You may have heard the buzzword "Thalidomide" when you came across your crazy anti-Vax aunt who participated in a Facebook discussion. An important theory in the anti-vaccine movement is that the vaccines given to babies cause them to grow up with autism. Thalidomide is often referred to as one of these ingredients. It is all incredibly reckless and untrue and is usually based on the "results" of a discredited gastroenterologist.

Thalidomide itself was used in the 1950s and 1960s as a cure for morning sickness in pregnant women. Whether it worked or not is not nearly as important as the fact that it hindered the development of key-stage blood vessels for the fetus. Five to nine weeks after the pregnancy, the expectant mothers usually took thalidomide, and in tens of thousands of cases this led to astonishing birth defects in the brain and limbs of their born babies. Only in 1961, the treatment with thalidomide was finally stopped, but the damage had clearly occurred already. If there was only one vaccine that prevents pharmaceutical companies from giving harmful products to humans.

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