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10 rarest diseases that you have never heard of



The “medical condition” is a broad term because it encompasses all diseases, disorders and all diseases. Many people are fully aware of some typical diseases like asthma, high blood pressure and diabetes.

However, some doctors do not have any unusual diseases. It can take years for these conditions to be properly diagnosed, especially when it comes to treatment.

Here are the 10 rarest diseases you have never heard of:

1. Water allergy

Rarest diseases - water allergy

Water is literally everywhere. It covers more or less 71% of the earth’s surface and of course our body consists mainly of water. It may seem crazy, but a water allergy is a real thing.

Activities like drinking water, swimming or showering may not be possible with this rare condition. So that the beehives can be treated after contact with water, doctors prescribe an antihistamine.

2. Sleeping Beauty Syndrome

Rarest diseases - Sleeping Beauty Syndrome

It is normal to be tired. In fact, the majority of people often feel tired all day long. For an average person to rejuvenate, it usually takes 20 minutes to nap. A person who can sleep up to 20 hours a day but still feels tired has Sleeping Beauty Syndrome.

Sleeping Beauty Disorder can also make the person dazed and confused. To have an active lifestyle and reduce drowsiness, stimulating pills are given.

3. Marie Antoinette syndrome

Rarest diseases - Marie Antoinette syndrome

Before the French Revolution, Marie Antoniette was the last queen of France. She was known throughout history for her white, large hair, her fashion and her lavish style. This rare condition suddenly turns the hair white; that’s why it was named after the infamous queen.

None of us want to have premature gray hair. Fortunately, the disease can be successfully treated with a good hair dye box or with steroids.

4. Hypertrichosis

Rarest diseases - hypertrichosis

For some, being hairy is appealing. Even so, excessive hair can be a symptom of hypertrichosis. Abnormal hair growth all over the body is a hallmark of this rare condition.

Hair growth can be seen all over the neck, face, back, legs or arms of the body. The cure is yet to be discovered, but hair removal procedures can reduce the effects of hypertrichosis.

5. Alice in Wonderland Syndrome

Rare diseases - Alice in Wonderland syndrome

Alice in Wonderland Syndrome takes its name from the film “Alice in Wonderland”, in which Alice shrinks after drinking the magic potion. This is the same feeling from people with AWS.

When a person has this, they can feel a lot smaller or a lot bigger compared to their actual size. Disorientation and distorted perception episodes have also been shown to be caused by AWS.

There is currently no cure. Making patients feel comfortable is the best treatment for this condition, according to the doctor’s recommendations.

6. Fibrodysplasia Ossificans Progressiva

Rarest diseases - Fibrodysplasia Ossifican

The soft tissue that gives the muscles the ability to rise and contract is the muscle tissue. A bone is slowly replacing an individual’s connective tissue, ligaments and muscle tissue with Fibrodysplasia ossificans progressiva (FOP).

Over time, FOP makes it impossible for a person to move. Most FOP patients become bedridden at the age of 20 and have an average life expectancy of 40 years.

7. Fish odor syndrome

Rarest diseases - fish smell syndrome

Don’t judge quickly if you smell an unusual stench of rotting fish. It could come from a person who has a rare medical condition.

Fish odor syndrome or trimethylaminuria can occur if the nitrogen-containing compounds cannot be broken down by the body. As a result, a person’s body odor becomes excessive. Smelly urine, aggressive sweating and bad breath are the possible side effects.

8. Cotard’s Deception

Rarest diseases - Cotard delusion

Did you feel like you don’t exist no matter what you do? Of course, the feeling is not good. A person with Cotard’s craze feels the same and much worse.

A person with Cotard Delusion has delusions that make them feel like they don’t exist or are already dead!

According to researchers, the most common diagnosis for people with Cotard craze is depression.

9. Capgra’s Deception

Rarest diseases - capgrass deception

Can you imagine living in a world where you always fear that an identical fraudster has replaced your special person? This fear is a reality for people with Capgras delusion.

According to some researchers, the cause of Capgra’s delusion is both cognitive and physical changes in the brain. There is currently no treatment or cure to effectively remove this type of deception.

10. Auto brewery syndrome

Rarest diseases - Auto Brewery Syndrome

It may sound crazy, but there is a disease that causes your body to naturally produce intoxicating amounts of ethanol. This causes a person to feel bloated, painful, and extremely tired.

Dietary carbohydrate reduction is one of the treatments for this rare Auto Brewery syndrome. It is also known that doctors have prescribed antifungals to stop endogenous fermentation production in the patient’s digestive system.


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