Scientists are back. This time they create new viruses and bacteria in their laboratories. Scientists usually prefer to alter existing or extinct bacteria and viruses to create new strains that defeat our immunity, vaccines and medicines.
Sometimes they prefer to create new viruses and bacteria from scratch. However, these strains are not always dangerous to humans, although they can be fatal to animals such as mice and even other bacteria.
University of Alberta scientists have developed Horsepox, a deadly virus closely related to equally fatal smallpox. Unlike smallpox, horses do not affect humans and are deadly only to horses.
Scientists developed the virus during a six-month study sponsored by pharmaceutical company Tonix. The researchers bought DNA pieces by mail order and arranged them to form the virus. The whole project was not expensive. The DNA parts from which the virus was made cost only $ 100,000.
The study caused a dilemma at the time of discovery. Other scientists were concerned that governments or even terrorists could use this knowledge to produce smallpox virus for biological weapons. A smallpox epidemic could be deadly for us today. We will not be vaccinated anymore because we eradicated the disease in 1980.
The researchers made it clear that they had developed the virus because they wanted to develop improved smallpox vaccines. Tonix later revealed that he had produced a smallpox vaccine with the horsepox virus.
Other scientists say the researchers could have pulled horsepox from wild horse populations instead of creating them from scratch. Tonix said that they did just that if they knew they had natural access to the virus.
Lead researcher David Evans, however, said they re-created the virus because Tonix was unable to commercialize the wild-born horsepox virus. 
9 Black Death
Between 1347 and 1351 million Europeans were attacked by a mysterious disease that killed over 50 million people. Today we know that this disease is the Black Death caused by the bacteria Yersinia pestis . Although Black Death is still nearby, it is not as powerful as it used to be.
Several years ago, researchers from several schools, including the University of Tübingen in Germany and McMaster University in Canada, recovered the deadly bacteria from DNA samples taken from the teeth of a victim who died during the plague. They only got 30 milligrams of the bacteria out of their teeth, but that was enough to restore them.
As a result, the researchers confirmed the relationship of the original bacteria to black death today. Some scientists have claimed that the bacteria are different strains but are now considered identical. Those we have today became less deadly after the mutation. 
Like their colleagues at the University of Alberta, scientists at the State University of New York have developed a deadly artificial virus by purchasing DNA by mail order. This time it's polio – and it's as effective as the natural one. Mice exposed to the artificial polio became as ill as they would have been with a natural polio.
The polio created in the laboratory was controversial among scientists. The researchers who produced it had taken their code from databases that were available to almost everyone. Other researchers fear that people with ulterior motive could develop their own artificial polio, which is much easier than other dangerous viruses like smallpox.
The genetic code of smallpox is 185,000 letters long, while polio is only 7,741 characters long. Although we are on the verge of eradicating polio, we fear that we still need to be vaccinated against the disease because it could be restored. 
Several years ago, researchers from the Australian National University and the Commonwealth Scientific and Industrial Research Organization (CSIRO) mistakenly produced a deadly mutated mouse epox strain. Mousepox is another deadly virus that belongs to the same family as horse and smallpox.
Researchers attempted to develop birth control for mice at the time they mistakenly created the virus. They inserted a gene that promoted the formation of interleukin 4 (IL-4) in the mouse epox, which they injected into some mice. The mice were vaccinated and should not be injured by the mouse pox.
Instead of rendering the mice infertile, as the researchers expected, the weakened virus became deadly, destroying the mice's immune system and killing them within nine days. The new Mousepox was so dangerous that it was resistant to vaccinations. Half of the other vaccinated mice exposed to the mutant mouse epox also died.
The researchers were so afraid of their invention that they did not want to publish their findings. They even met with the Australian military to make sure the release was safe. [19459011
Scientists fear that human smallpox could also mutate and become fatal if IL-4 were injected. However, they are uncertain because no one has tried yet. We know that it is only a matter of time before some scientists do this. SARS 2.0
SARS is a deadly virus. More than 700 people were killed during a SARS epidemic that infected 8,000 people in 29 countries between 2002 and 2003. Now scientists have made it deadly.
The new mutant SARS virus was discovered by a group of researchers led by Dr. Ing. Ralph creates Baric from the University of North Carolina. They call it SARS 2.0. The researchers developed the virus by adding some protein to the naturally occurring SARS. SARS 2.0 is immune to vaccines and treatments to cure the naturally occurring SARS virus. 
The team said the research was needed because the natural SARS virus could mutate and become immune to our vaccines. By creating a more deadly and mutated virus, we could develop stronger vaccines to save us from a more deadly SARS epidemic – that is, when the natural SARS ever mutates.
But other scientists are worried that SARS 2.0, which is supposed to save us from a deadly SARS epidemic, could trigger this epidemic if it ever escapes from the lab.
5 MERS-Rabies Virus Hybrid
] Scientists have developed a MERS rabies hybrid virus. The idea is to use the virus to develop a vaccine that protects us from both viruses. Rabies is a deadly disease that can be transmitted to humans through the bite of infected dogs that normally have the virus in their saliva.
MERS syndrome (MERS) is a new virus that occurred in Saudi Arabia a few years ago. It is closely related to SARS and spreads from bats to camels to humans. MERS infected 1,800 people at the time of its first epidemic, killing over 630 people. The death toll is around 35 percent.
As mentioned earlier, SARS infected more than 8,000 people during an epidemic in 2003, but killed just over 700 people. Although SARS has caused more deaths in absolute terms, the death rate is lower than MERS. Only about 10 percent of SARS victims died. Right now we do not have a vaccine against MERS.
To make the MERS rabies hybrid, researchers took some proteins from the MERS virus and added them to rabies. They used the new virus to develop a new vaccine that made mice resistant to rabies and MERS. They believe that the vaccine can also be used on humans and camels who are at risk for MERS. 
Phi-X174 is another artificial virus we have produced in laboratories. It was founded by researchers from the Institute of Biological Energy Alternatives in Rockville, Maryland. The researchers modeled the artificial virus after the natural PhiX virus. PhiX is a bacteriophage, a category of viruses that infect and kill bacteria. However, it does not affect humans. 
The researchers created the artificial virus in 14 days, but they are so similar to the natural virus that it is impossible to tell them apart. The researchers hope that the new virus is the first step in the development of mutant and artificial bacteria that can be used for human benefit.
3 Unnamed Virus
Researchers at University College London and the National Physical Laboratory have created an unidentified virus that kills bacteria and behaves like a true virus. Like Phi-X174, it is a bacteriophage, but more deadly.
The unnamed virus attacks bacteria in the environment. Within seconds, it breaks into smaller pieces that accumulate on the body of the bacteria and form holes. The holes grow larger quickly and force the bacteria to deliver their contents. The bacteria die soon afterwards.
Despite its uncanny potency, the unnamed virus is not dangerous to humans and has not attacked human cells during the test. However, it could invade human cells just like natural viruses. The researchers hope the results will be used to treat and study bacterial diseases in humans. The virus could also be used to alter the human gene. 
2 Bird Flu
Some Dutch scientists have created a mutant and deadly version of already fatal bird flu. Natural avian influenza is not easily transmitted between humans. The researchers, however, changed it so that it was possible. To test their new virus, researchers have exposed some ferrets to it. Ferrets were selected because they had similar symptoms of bird flu as humans.
Ten generations later, the already-altered virus mutated again and became airborne. Natural avian flu is not an airborne disease. The study was controversial in the scientific community. This is even more so when the Dutch researchers tried to publicize the process of causing the deadly virus. [19459011
Although scientists fear that terrorists could use the study to create a deadly biological weapon that could kill half of the world's population, the researchers involved say the study was needed to point us to a mutant To prepare bird flu epidemic.
1 H1N1 virus
In 1918, the world experienced the death of a flu epidemic. This was the H1N1 virus. By that time, up to 100 million people had died. The flu seeped blood into the lungs of the victims. They released blood from the nose and mouth before drowning in the blood in their lungs.
The flu returned in 2009. It was less deadly, though mutated and deadlier than it should have been. Scientist Yoshihiro Kawaoka took samples of the mutant strain that caused the 2009 epidemic and turned it into a deadly strain resistant to vaccines. This burden was similar to that which triggered the 1918 epidemic. 
At the time, Kawaoka did not intend to produce a more deadly version of the flu. He just wanted to create the original version of the flu to investigate how it's mutated and can bypass our immunity. The deadly virus is stored in a laboratory and could result in death if released.